Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
nfrA2Nitroreductase family protein; KEGG: fnu:FN1254 1.3e-26 oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase K00357; COG: COG0778 Nitroreductase; Psort location: Cytoplasmic, score: 8.87; ORF located using Blastx. (247 aa)    
Predicted Functional Partners:
EDS07719.1
Hypothetical protein; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.645
yybR
Transcriptional regulator, HxlR family; KEGG: eca:ECA0039 0.0056 rpoZ; DNA-directed RNA polymerase omega chain K03060; COG: COG1733 Predicted transcriptional regulators.
 
     0.611
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.605
GloA
Glyoxalase family protein; KEGG: fnu:FN0356 3.8e-36 lactoylglutathione lyase K01759; COG: COG0346 Lactoylglutathione lyase and related lyases; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.572
tadA_1
Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
 0.432
EDS08694.1
ABC-2 type transporter; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.425
EDS07720.1
Hypothetical protein; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.425
EDS05533.1
Hypothetical protein.
  
  
 0.425
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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