Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
graR_2Response regulator receiver domain protein; KEGG: eci:UTI89_C0420 1.2e-27 phoB; positive response regulator for pho regulon K07657; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. (227 aa)    
Predicted Functional Partners:
graS_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo1741 1.4e-29 similar to two-component sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.954
bceB_2
Efflux ABC transporter, permease protein; KEGG: msm:MSMEG_1710 0.0077 ribose transport system permease protein RbsC; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.883
yxdL_4
KEGG: lwe:lwe2133 8.4e-64 ABC transporter, ATP-binding protein K06020; COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
     0.843
graS_3
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: cpe:CPE0841 1.0e-65 two-component sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.754
walR_7
Transcriptional regulatory protein, C-terminal domain protein; KEGG: ava:Ava_3369 8.5e-16 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
     0.729
MprB
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
   0.712
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.704
graS_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spd:SPD_1445 4.7e-54 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.689
EDS08419.1
ABC transporter, solute-binding protein; COG: COG1653 ABC-type sugar transport system, periplasmic component.
       0.658
walK_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: btk:BT9727_4271 4.8e-61 resE; sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
  
   0.653
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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