Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
UdkPhosphoribulokinase/uridine kinase family protein; KEGG: ctc:CTC00344 2.9e-125 uridine kinase K00876; COG: COG0572 Uridine kinase; Psort location: Cytoplasmic, score: 8.87. (555 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.985
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.937
cmk
Cytidylate kinase; KEGG: ljo:LJ1089 2.3e-52 cytidylate kinase K00945; COG: COG0283 Cytidylate kinase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.932
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.927
surE
KEGG: mth:MTH1435 4.0e-34 surE; acid phosphatase K03787; COG: COG0496 Predicted acid phosphatase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.922
pyrF
KEGG: blo:BL0791 7.1e-67 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.916
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
    
 0.914
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    
 0.903
hit
Protein hit; KEGG: lsl:LSL_0477 3.2e-23 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) K01518; COG: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; Psort location: Cytoplasmic, score: 8.87.
   
  0.764
trmK
Hypothetical protein; KEGG: fnu:FN0907 0.0071 ribosomal RNA small subunit methyltransferase C K00564; COG: COG2384 Predicted SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 8.87.
       0.747
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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