Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdxB-3KEGG: hwa:HQ2066A 2.6e-60 serA; phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (345 aa)    
Predicted Functional Partners:
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 0.965
EDS05086.1
Putative homoserine kinase; KEGG: swo:Swol_1301 4.8e-100 phosphoglycerate mutase K01834; COG: COG3635 Predicted phosphoglycerate mutase, AP superfamily; Psort location: Cytoplasmic, score: 8.87.
 
  
  0.912
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.902
xylB_8
Carbohydrate kinase, FGGY family protein; KEGG: cac:CAC2612 1.8e-63 xylB; xylulose kinase K00854; COG: COG1070 Sugar (pentulose and hexulose) kinases; Psort location: Cytoplasmic, score: 8.87; Belongs to the FGGY kinase family.
 
    0.827
fucA_2
Putative L-ribulose-5-phosphate 4-epimerase; KEGG: chy:CHY_1555 3.9e-43 fucA2; L-fuculose phosphate aldolase K01628; COG: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; Psort location: Cytoplasmic, score: 8.87.
  
    0.721
pdxB-2
KEGG: hwa:HQ2066A 3.5e-58 serA; phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.65; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
    
0.714
XylB_7
KEGG: tma:TM0284 3.5e-42 sugar kinase, FGGY family K00854; COG: COG1070 Sugar (pentulose and hexulose) kinases; Psort location: Cytoplasmic, score: 8.87.
  
    0.693
DeoR_1
Putative sugar-binding domain protein; KEGG: rde:RD1_3614 2.8e-33 glycerone kinase, putative K00863; COG: COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
     0.691
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  0.542
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 
 0.528
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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