Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
lepBSignal peptidase I; KEGG: spk:MGAS9429_Spy0112 4.5e-26 signal peptidase I K03100; Psort location: Cytoplasmic, score: 8.87; Belongs to the peptidase S26 family. (182 aa)    
Predicted Functional Partners:
EDS07857.1
Pilin isopeptide linkage domain protein.
 
     0.813
EDS07861.1
Hypothetical protein.
       0.780
srtB
Sortase, SrtB family; COG: COG4509 Uncharacterized protein conserved in bacteria.
 
     0.769
EDS07862.1
Hypothetical protein; KEGG: chu:CHU_1335 0.00057 CHU large protein; endoglucanase-related protein, glucosyl hydrolase family 9 protein K01238.
     
 0.746
EDS07863.1
Hypothetical protein.
       0.624
EDS07262.1
Pilin isopeptide linkage domain protein; KEGG: cal:orf19.4072 0.0010 HYR10; similar to cell surface flocculin K01186.
 
     0.591
EDS07260.1
Hypothetical protein.
 
     0.590
EDS07859.1
Pilin isopeptide linkage domain protein; KEGG: cal:orf19.4072 0.0015 HYR10; similar to cell surface flocculin K01186.
       0.553
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.553
minE
Putative cell division topological specificity factor MinE; Psort location: Cytoplasmic, score: 8.87.
   
    0.550
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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