Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pnuCCOG: COG3201 Nicotinamide mononucleotide transporter; Psort location: CytoplasmicMembrane, score: 9.99. (230 aa)    
Predicted Functional Partners:
draG_2
ADP-ribosylglycohydrolase; KEGG: ser:SERP2218 3.6e-79 ADP-ribosylglycohydrolase, putative K05521; COG: COG1397 ADP-ribosylglycohydrolase.
 
     0.843
rbsK_2
Kinase, PfkB family; KEGG: cdi:DIP0655 9.2e-19 putative ribokinase K00852; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score: 9.98; Belongs to the carbohydrate kinase PfkB family.
 
   
 0.815
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  
  
 0.763
NadB
FAD binding domain protein; KEGG: fnu:FN0009 4.8e-100 L-aspartate oxidase K00278; COG: COG0029 Aspartate oxidase; Psort location: Cytoplasmic, score: 9.36.
   
  
 0.730
YurK_2
UbiC transcription regulator-associated domain protein; KEGG: mtc:MT0817 2.6e-14 dihydrolipoamide dehydrogenase K00382; COG: COG2188 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
 
     0.576
EDS06822.1
GBS Bsp-like repeat protein; COG: NOG18564 non supervised orthologous group.
  
     0.480
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
     
 0.476
pncA
Isochorismatase family protein; KEGG: pab:PAB1720 3.7e-15 nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.456
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.422
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.416
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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