close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dxs_2KEGG: rha:RHA1_ro00814 3.5e-58 possible transketolase, C-terminal subunit K00615; COG: COG3958 Transketolase, C-terminal subunit; Psort location: Cytoplasmic, score: 8.87. (327 aa)    
Predicted Functional Partners:
Tkt_1
Transketolase, thiamine diphosphate binding domain protein; KEGG: lmf:LMOf2365_1053 7.1e-83 transketolase, N-terminal subunit K00615; COG: COG3959 Transketolase, N-terminal subunit; Psort location: Cytoplasmic, score: 8.87.
 0.999
fas2
Transketolase, thiamine diphosphate binding domain protein; KEGG: mta:Moth_0236 1.5e-48 transketolase-like K00615; COG: COG3959 Transketolase, N-terminal subunit; Psort location: Cytoplasmic, score: 8.87.
 0.999
tktA
Transketolase, thiamine diphosphate binding domain protein; KEGG: cpe:CPE0296 8.5e-87 tktN; transketolase N-terminal section K00615; COG: COG3959 Transketolase, N-terminal subunit; Psort location: Cytoplasmic, score: 8.87.
 0.999
rpe
KEGG: cno:NT01CX_2237 3.6e-56 ribulose-phosphate 3-epimerase K01783; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.962
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.924
dxs_1
Transketolase, C-terminal domain protein; KEGG: lmo:lmo1033 1.8e-86 similar to transketolase K00615; COG: COG3958 Transketolase, C-terminal subunit.
  
  
 
0.917
dxs_3
Transketolase, pyridine binding domain protein; KEGG: cno:NT01CX_1268 1.3e-97 transketolase, C-terminal subunit K00615; COG: COG3958 Transketolase, C-terminal subunit; Psort location: Cytoplasmic, score: 8.87.
  
  
 
0.912
fsa
Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.909
pgi
KEGG: bcl:ABC2906 1.4e-164 pgi; glucose-6-phosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.98; Belongs to the GPI family.
     
 0.903
prs
Ribose-phosphate diphosphokinase; KEGG: cac:CAC0819 1.3e-97 phosphoribosylpyrophosphate synthetase K00948; COG: COG0462 Phosphoribosylpyrophosphate synthetase; Psort location: Cytoplasmic, score: 8.87; Belongs to the ribose-phosphate pyrophosphokinase family.
    
  0.902
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (16%) [HD]