Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hflKSPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 9.1e-51 membrane protease subunits, stomatin/prohibitin homologs K01423; COG: COG0330 Membrane protease subunits, stomatin/prohibitin homologs; Psort location: Cytoplasmic, score: 8.87. (313 aa)    
Predicted Functional Partners:
EDS07946.1
COG: COG1585 Membrane protein implicated in regulation of membrane protease activity; Psort location: CytoplasmicMembrane, score: 7.63.
 
 
 0.974
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.790
EDS07942.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.744
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
       0.738
coaX
Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.728
EDS06358.1
COG: COG4877 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.624
EDS07947.1
Putative RNA methyltransferase, TrmH family, group 3; KEGG: gka:GK2709 6.1e-38 rRNA methylase K03437; COG: COG0566 rRNA methylases; Psort location: Cytoplasmic, score: 8.87.
   
   0.622
EDS08296.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
    
 0.603
EDS07141.1
Hypothetical protein; KEGG: mmr:Mmar10_0193 4.0e-08 ATP-dependent metalloprotease FtsH; COG: COG0465 ATP-dependent Zn proteases; Belongs to the AAA ATPase family.
   
 0.551
hflB
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.551
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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