Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemN_1Radical SAM domain protein; KEGG: cpe:CPE1645 2.5e-112 Mg-protoporphyrin IX monomethyl ester oxidative cyclase K04034; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (588 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.791
EDS07975.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.639
thiL
Hypothetical protein; KEGG: mth:MTH1374 9.2e-06 phosphoribosylformylglycinamidine synthase II K01952; COG: COG0309 Hydrogenase maturation factor; Psort location: CytoplasmicMembrane, score: 7.80.
 
     0.542
vanW
G5 domain protein; KEGG: rno:64550 0.0099 Top1; topoisomerase (DNA) I K03163; COG: COG2720 Uncharacterized vancomycin resistance protein; Psort location: Cytoplasmic, score: 8.87.
       0.482
EDS05074.1
COG: COG0629 Single-stranded DNA-binding protein; Psort location: Cytoplasmic, score: 8.87.
  
    0.451
EDS07970.1
Transcriptional regulator, AsnC family; KEGG: sat:SYN_02590 0.0048 anthranilate phosphoribosyltransferase K00766; COG: COG1522 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
  
    0.445
patA_1
Aminotransferase, class I/II; KEGG: cpr:CPR_0701 1.1e-123 aspartate aminotransferase K00811; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score: 8.87.
       0.430
EDS08066.1
Hypothetical protein; COG: NOG14690 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
   
    0.400
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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