| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS08013.1 | EDS08014.1 | CLOSCI_01028 | CLOSCI_01029 | Hypothetical protein; COG: COG3593 Predicted ATP-dependent endonuclease of the OLD family; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: cno:NT01CX_0497 0.0013 pflC; pyruvate formate-lyase K00538. | 0.477 |
| EDS08013.1 | nrdG | CLOSCI_01028 | CLOSCI_01030 | Hypothetical protein; COG: COG3593 Predicted ATP-dependent endonuclease of the OLD family; Psort location: Cytoplasmic, score: 8.87. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.445 |
| EDS08014.1 | EDS08013.1 | CLOSCI_01029 | CLOSCI_01028 | Hypothetical protein; KEGG: cno:NT01CX_0497 0.0013 pflC; pyruvate formate-lyase K00538. | Hypothetical protein; COG: COG3593 Predicted ATP-dependent endonuclease of the OLD family; Psort location: Cytoplasmic, score: 8.87. | 0.477 |
| EDS08014.1 | nrdD | CLOSCI_01029 | CLOSCI_01031 | Hypothetical protein; KEGG: cno:NT01CX_0497 0.0013 pflC; pyruvate formate-lyase K00538. | KEGG: lla:L70400 2.3e-116 nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87. | 0.535 |
| EDS08014.1 | nrdG | CLOSCI_01029 | CLOSCI_01030 | Hypothetical protein; KEGG: cno:NT01CX_0497 0.0013 pflC; pyruvate formate-lyase K00538. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.714 |
| folE | nrdD | CLOSCI_01146 | CLOSCI_01031 | GTP cyclohydrolase I; KEGG: cpe:CPE1019 4.3e-60 mtrA; GTP cyclohydrolase K01495; COG: COG0302 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 8.87. | KEGG: lla:L70400 2.3e-116 nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87. | 0.800 |
| folE | nrdD-2 | CLOSCI_01146 | CLOSCI_01639 | GTP cyclohydrolase I; KEGG: cpe:CPE1019 4.3e-60 mtrA; GTP cyclohydrolase K01495; COG: COG0302 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 8.87. | KEGG: tde:TDE1331 2.6e-220 nrdD; anaerobic ribonucleoside triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87. | 0.811 |
| folE | nrdG | CLOSCI_01146 | CLOSCI_01030 | GTP cyclohydrolase I; KEGG: cpe:CPE1019 4.3e-60 mtrA; GTP cyclohydrolase K01495; COG: COG0302 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 8.87. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.520 |
| guaA | guaA-2 | CLOSCI_03102 | CLOSCI_03505 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | 0.930 |
| guaA | nrdE1 | CLOSCI_03102 | CLOSCI_02889 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.765 |
| guaA | nrdG | CLOSCI_03102 | CLOSCI_01030 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.536 |
| guaA-2 | guaA | CLOSCI_03505 | CLOSCI_03102 | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.930 |
| guaA-2 | nrdE1 | CLOSCI_03505 | CLOSCI_02889 | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.765 |
| guaA-2 | nrdG | CLOSCI_03505 | CLOSCI_01030 | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.536 |
| hadI | nrdD-2 | CLOSCI_00653 | CLOSCI_01639 | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 1.6e-18 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | KEGG: tde:TDE1331 2.6e-220 nrdD; anaerobic ribonucleoside triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87. | 0.435 |
| hadI | nrdE1 | CLOSCI_00653 | CLOSCI_02889 | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 1.6e-18 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.416 |
| hadI | nrdG | CLOSCI_00653 | CLOSCI_01030 | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 1.6e-18 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.449 |
| nrdD | EDS08014.1 | CLOSCI_01031 | CLOSCI_01029 | KEGG: lla:L70400 2.3e-116 nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: cno:NT01CX_0497 0.0013 pflC; pyruvate formate-lyase K00538. | 0.535 |
| nrdD | folE | CLOSCI_01031 | CLOSCI_01146 | KEGG: lla:L70400 2.3e-116 nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87. | GTP cyclohydrolase I; KEGG: cpe:CPE1019 4.3e-60 mtrA; GTP cyclohydrolase K01495; COG: COG0302 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 8.87. | 0.800 |
| nrdD | nrdD-2 | CLOSCI_01031 | CLOSCI_01639 | KEGG: lla:L70400 2.3e-116 nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87. | KEGG: tde:TDE1331 2.6e-220 nrdD; anaerobic ribonucleoside triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87. | 0.913 |