close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gph_3Putative phosphoglycolate phosphatase, bacterial; KEGG: tde:TDE2716 3.7e-47 HAD-superfamily hydrolase, subfamily IA K01091; COG: COG0546 Predicted phosphatases; Psort location: Cytoplasmic, score: 8.87. (221 aa)    
Predicted Functional Partners:
EDS08080.1
Haloacid dehalogenase-like hydrolase; KEGG: smu:SMU.1254 7.6e-63 conserved hypothetical protein K01091; COG: COG0546 Predicted phosphatases; Psort location: Cytoplasmic, score: 8.87.
  
  
 
0.925
pdxB-5
KEGG: mja:MJ1018 3.9e-59 serA; phosphoglycerate dehydrogenase (SerA) K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.903
pdxB-6
KEGG: cff:CFF8240_1663 7.1e-67 hprA; glycerate dehydrogenase K00018; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.902
gph_1
HAD hydrolase, family IA, variant 1; KEGG: lil:LA2702 1.6e-12 phosphoglycolate phosphatase K01091; COG: COG0546 Predicted phosphatases; Psort location: Cytoplasmic, score: 8.87.
     
  0.900
EDS07651.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.680
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
     
 0.601
sigG
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.598
EDS05841.1
Hypothetical protein; COG: NOG18663 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
      0.524
moaA_2
Molybdenum cofactor biosynthesis protein A family protein; KEGG: mka:MK1086 0.0025 ferredoxin domain fused to pyruvate-formate lyase-activating enzyme K04069; COG: COG2896 Molybdenum cofactor biosynthesis enzyme; Psort location: Cytoplasmic, score: 8.87.
  
    0.519
PurL
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.431
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.