Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (174 aa)    
Predicted Functional Partners:
purH
AICARFT/IMPCHase bienzyme; KEGG: sce:YLR028C 1.4e-125 ADE16; AICAR transformylase/IMP cyclohydrolase K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.87.
  
 0.964
purB
Adenylosuccinate lyase; KEGG: cno:NT01CX_2118 9.8e-173 purB; adenylosuccinate lyase K01756; COG: COG0015 Adenylosuccinate lyase; Psort location: Cytoplasmic, score: 8.87.
  
 0.958
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.934
deoD
KEGG: bcl:ABC4021 1.3e-76 deoD; purine-nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 8.87.
    
 0.918
surE
KEGG: mth:MTH1435 4.0e-34 surE; acid phosphatase K03787; COG: COG0496 Predicted acid phosphatase; Psort location: Cytoplasmic, score: 8.87.
    
 0.916
ade
Adenine deaminase; KEGG: cac:CAC0887 4.4e-122 adeC; adenine deaminase K01486; COG: COG1001 Adenine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.908
adeC_1
Putative adenine deaminase; KEGG: cpe:CPE1268 8.7e-133 adeC; probable adenine deaminase K01486; COG: COG1001 Adenine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.908
yfiH
Conserved hypothetical protein, YfiH family; COG: COG1496 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.904
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
   
 
 0.818
PurL
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.815
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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