Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hom_2KEGG: chy:CHY_1912 6.1e-125 hom; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87. (428 aa)    
Predicted Functional Partners:
asd
KEGG: lsl:LSL_0313 7.3e-145 asd; aspartate-semialdehyde dehydrogenase K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
  
 0.955
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
 
 0.939
metH_3
KEGG: ctc:CTC01806 1.4e-203 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.938
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.924
hom_1
KEGG: tte:TTE2620 5.9e-79 thrA2; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
  
  
 
0.910
ilvE
KEGG: cac:CAC1479 1.3e-152 ilvE; branched-chain-amino-acid transaminase (ilvE) K00826; COG: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.903
lysC_1
KEGG: chy:CHY_1909 1.7e-120 aspartate kinase, monofunctional class K00928; COG: COG0527 Aspartokinases; Belongs to the aspartokinase family.
 
 0.895
thrC
Threonine synthase; KEGG: cac:CAC0999 4.3e-163 thrC; threonine synthase K01733; COG: COG0498 Threonine synthase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.866
cysE
KEGG: gka:GK0084 1.1e-63 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.850
mgl_1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: bth:BT2387 1.2e-167 O-acetylhomoserine (thiol)-lyase K01740; COG: COG2873 O-acetylhomoserine sulfhydrylase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.842
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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