| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AdhE | EDS07681.1 | CLOSCI_02188 | CLOSCI_01154 | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.799 |
| AdhE | betB | CLOSCI_02188 | CLOSCI_01805 | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Aldehyde dehydrogenase (NAD) family protein; KEGG: tde:TDE0080 1.3e-175 gbsA; betaine aldehyde dehydrogenase K00130; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.967 |
| AdhE | nifJ | CLOSCI_02188 | CLOSCI_01585 | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87. | 0.981 |
| EDS07681.1 | AdhE | CLOSCI_01154 | CLOSCI_02188 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.799 |
| EDS07681.1 | EDS07682.1 | CLOSCI_01154 | CLOSCI_01155 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | 0.834 |
| EDS07681.1 | EDS07913.1 | CLOSCI_01154 | CLOSCI_00927 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | 0.532 |
| EDS07681.1 | EDS07914.1 | CLOSCI_01154 | CLOSCI_00928 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Flavodoxin; KEGG: rsp:RSP_3191 2.2e-09 fprA; flavodoxin; COG: COG0716 Flavodoxins. | 0.784 |
| EDS07681.1 | PurL | CLOSCI_01154 | CLOSCI_01211 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | 0.612 |
| EDS07681.1 | betB | CLOSCI_01154 | CLOSCI_01805 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Aldehyde dehydrogenase (NAD) family protein; KEGG: tde:TDE0080 1.3e-175 gbsA; betaine aldehyde dehydrogenase K00130; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.446 |
| EDS07681.1 | folA | CLOSCI_01154 | CLOSCI_01157 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.434 |
| EDS07681.1 | nifJ | CLOSCI_01154 | CLOSCI_01585 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87. | 0.605 |
| EDS07681.1 | slyA_2 | CLOSCI_01154 | CLOSCI_01153 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Transcriptional regulator, MarR family; COG: NOG16844 non supervised orthologous group. | 0.480 |
| EDS07681.1 | thyA | CLOSCI_01154 | CLOSCI_01156 | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.434 |
| EDS07682.1 | EDS07681.1 | CLOSCI_01155 | CLOSCI_01154 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.834 |
| EDS07682.1 | folA | CLOSCI_01155 | CLOSCI_01157 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.505 |
| EDS07682.1 | slyA_2 | CLOSCI_01155 | CLOSCI_01153 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Transcriptional regulator, MarR family; COG: NOG16844 non supervised orthologous group. | 0.419 |
| EDS07682.1 | thyA | CLOSCI_01155 | CLOSCI_01156 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.497 |
| EDS07913.1 | EDS07681.1 | CLOSCI_00927 | CLOSCI_01154 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.532 |
| EDS07913.1 | EDS07914.1 | CLOSCI_00927 | CLOSCI_00928 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Flavodoxin; KEGG: rsp:RSP_3191 2.2e-09 fprA; flavodoxin; COG: COG0716 Flavodoxins. | 0.695 |
| EDS07914.1 | EDS07681.1 | CLOSCI_00928 | CLOSCI_01154 | Flavodoxin; KEGG: rsp:RSP_3191 2.2e-09 fprA; flavodoxin; COG: COG0716 Flavodoxins. | Hypothetical protein; COG: NOG13233 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.784 |