Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS07685.1Glycosyltransferase, group 1 family protein; KEGG: mth:MTH450 1.4e-15 LPS biosynthesis RfbU related protein K00754; COG: COG0438 Glycosyltransferase; Psort location: CytoplasmicMembrane, score: 9.76. (401 aa)    
Predicted Functional Partners:
WcaJ
KEGG: tcx:Tcr_1675 1.8e-70 undecaprenyl-phosphate galactosephosphotransferase K03606; COG: COG2148 Sugar transferases involved in lipopolysaccharide synthesis; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.836
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.784
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.778
YdjZ_2
SNARE-like domain protein; KEGG: hch:HCH_01003 6.6e-14 probable mercuric reductase K00520; COG: COG0398 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.675
glgB
KEGG: bcz:BCZK4621 1.2e-121 glgB; glycogen branching enzyme K00700; COG: COG0296 1,4-alpha-glucan branching enzyme; Psort location: Cytoplasmic, score: 8.87.
   
 0.651
glgB-2
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
 0.651
rfbC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.592
EDS06480.1
Polysaccharide biosynthesis protein; COG: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.589
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
  
 0.553
EDS05398.1
Hypothetical protein; KEGG: sat:SYN_00363 2.6e-20 glutamate synthase [NADPH] small chain K00264; COG: COG0247 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87.
  
     0.545
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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