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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEKEGG: cac:CAC1479 1.3e-152 ilvE; branched-chain-amino-acid transaminase (ilvE) K00826; COG: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Psort location: Cytoplasmic, score: 8.87. (372 aa)    
Predicted Functional Partners:
ilvD
KEGG: chy:CHY_0516 3.7e-196 ilvD; dihydroxy-acid dehydratase K01687; COG: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Psort location: Cytoplasmic, score: 8.87; Belongs to the IlvD/Edd family.
  
 0.992
leuA
Putative 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.978
hom_2
KEGG: chy:CHY_1912 6.1e-125 hom; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.911
ilvB-2
Acetolactate synthase, large subunit, biosynthetic type; KEGG: mac:MA3792 1.9e-153 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.903
hom_1
KEGG: tte:TTE2620 5.9e-79 thrA2; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.901
ilvA
KEGG: fnu:FN1411 6.2e-116 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase.
  
 
 0.891
ilvN-2
Acetolactate synthase, small subunit; KEGG: pha:PSHAb0463 1.8e-29 ilvH; acetolactate synthase isozyme III small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.851
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.815
pflB
KEGG: bce:BC0491 6.8e-268 formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
     
  0.800
pflB-2
KEGG: cya:CYA_0477 9.2e-264 pflB; formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
     
  0.800
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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