STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS07693.1Hypothetical protein; KEGG: ana:alr1121 5.7e-08 two-component hybrid sensor and regulator; COG: COG2409 Predicted drug exporters of the RND superfamily. (758 aa)    
Predicted Functional Partners:
ydfJ
Hypothetical protein; COG: COG1033 Predicted exporters of the RND superfamily; Psort location: CytoplasmicMembrane, score: 9.99.
   
 0.975
yvdT_2
Transcriptional regulator, TetR family; KEGG: bcl:ABC2937 0.00028 NADH dehydrogenase K03885; COG: COG1309 Transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.788
DesVI
Methyltransferase domain protein; KEGG: bce:BC4326 3.0e-45 methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87.
       0.522
hslO
Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.515
EDS07697.1
Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
    0.507
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
       0.499
EDS07690.1
Hypothetical protein.
       0.472
mprF-2
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
     0.463
FruA
KEGG: cpr:CPR_0550 3.4e-163 fructose specific permease K00890; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 10.00.
   
 
 0.411
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.