close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tcdAThiF family protein; KEGG: cal:orf19.2115 2.9e-24 molybdopterin-converting factor; COG: COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; Psort location: Cytoplasmic, score: 8.87. (240 aa)    
Predicted Functional Partners:
EDS07704.1
ATPase, AAA family; KEGG: ava:Ava_B0112 7.4e-120 ATPase K00961:K07478; COG: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; Psort location: Cytoplasmic, score: 8.87.
       0.701
pgdA
Polysaccharide deacetylase; KEGG: spn:SP_1479 4.3e-37 peptidoglycan N-acetylglucosamine deacetylase A K01463; COG: COG0726 Predicted xylanase/chitin deacetylase; Psort location: Extracellular, score: 9.57.
       0.672
csoR_2
COG: COG1937 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
       0.607
MepS
NlpC/P60 family protein; KEGG: psp:PSPPH_0470 5.8e-10 NLP/P60 family protein K01183; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: Extracellular, score: 9.73.
     
 0.499
EDS06283.1
NlpC/P60 family protein; KEGG: baa:BA_0322 2.0e-14 NLP/P60 family K01446; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: Extracellular, score: 9.95.
      
 0.497
LytF
NlpC/P60 family protein; KEGG: psp:PSPPH_0470 1.7e-17 NLP/P60 family protein K01183; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: Extracellular, score: 9.95.
      
 0.497
ripA
NlpC/P60 family protein; KEGG: bce:BC5234 1.5e-12 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: Extracellular, score: 9.95.
      
 0.497
thiS
COG: COG2104 Sulfur transfer protein involved in thiamine biosynthesis; Psort location: Cytoplasmic, score: 8.87.
  
   0.475
mepA_4
MATE efflux family protein; COG: COG0534 Na+-driven multidrug efflux pump; Psort location: CytoplasmicMembrane, score: 9.99.
       0.467
ThiF
ThiF family protein; KEGG: eca:ECA0230 1.2e-34 thiF; thiamine biosynthesis adenylyltransferase K03148; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; Psort location: Cytoplasmic, score: 8.87.
 
 
0.410
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (26%) [HD]