EDS07714.1 protein (Clostridium scindens) - STRING interaction network

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Score

EDS07714.1

Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518. (80 aa)

Predicted Functional Partners:

LplA

0.773

hrcA

0.520

grpE

0.520

EDS07712.1

0.459

dnaK

0.441

Your Current Organism:

Clostridium scindens

NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDS07712.1	EDS07714.1	CLOSCI_01185	CLOSCI_01187	Hypothetical protein.	Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518.	0.459
EDS07712.1	LplA	CLOSCI_01185	CLOSCI_01186	Hypothetical protein.	KEGG: ctc:CTC02045 6.4e-66 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.	0.459
EDS07714.1	EDS07712.1	CLOSCI_01187	CLOSCI_01185	Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518.	Hypothetical protein.	0.459
EDS07714.1	LplA	CLOSCI_01187	CLOSCI_01186	Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518.	KEGG: ctc:CTC02045 6.4e-66 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.	0.773
EDS07714.1	dnaK	CLOSCI_01187	CLOSCI_01190	Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.441
EDS07714.1	grpE	CLOSCI_01187	CLOSCI_01189	Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.520
EDS07714.1	hrcA	CLOSCI_01187	CLOSCI_01188	Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518.	Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.	0.520
LplA	EDS07712.1	CLOSCI_01186	CLOSCI_01185	KEGG: ctc:CTC02045 6.4e-66 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.	Hypothetical protein.	0.459
LplA	EDS07714.1	CLOSCI_01186	CLOSCI_01187	KEGG: ctc:CTC02045 6.4e-66 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.	Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518.	0.773
LplA	dnaK	CLOSCI_01186	CLOSCI_01190	KEGG: ctc:CTC02045 6.4e-66 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.483
LplA	grpE	CLOSCI_01186	CLOSCI_01189	KEGG: ctc:CTC02045 6.4e-66 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.546
LplA	hrcA	CLOSCI_01186	CLOSCI_01188	KEGG: ctc:CTC02045 6.4e-66 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.	Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.	0.531
dnaK	EDS07714.1	CLOSCI_01190	CLOSCI_01187	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518.	0.441
dnaK	LplA	CLOSCI_01190	CLOSCI_01186	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	KEGG: ctc:CTC02045 6.4e-66 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.	0.483
dnaK	grpE	CLOSCI_01190	CLOSCI_01189	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.999
dnaK	hrcA	CLOSCI_01190	CLOSCI_01188	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.	0.987
grpE	EDS07714.1	CLOSCI_01189	CLOSCI_01187	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	Hypothetical protein; KEGG: noc:Noc_1415 0.0011 NUDIX hydrolase K01518.	0.520
grpE	LplA	CLOSCI_01189	CLOSCI_01186	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	KEGG: ctc:CTC02045 6.4e-66 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.	0.546
grpE	dnaK	CLOSCI_01189	CLOSCI_01190	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.999
grpE	hrcA	CLOSCI_01189	CLOSCI_01188	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.	0.992