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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FixLATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tma:TM1359 1.6e-21 sensor histidine kinase K02486; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: CytoplasmicMembrane, score: 10.00. (609 aa)    
Predicted Functional Partners:
SrfAA
AMP-binding enzyme; KEGG: ava:Ava_1613 5.8e-204 non-ribosomal peptide synthase K00644; COG: COG1020 Non-ribosomal peptide synthetase modules and related proteins; Psort location: Cytoplasmic, score: 9.96; Belongs to the ATP-dependent AMP-binding enzyme family.
 
   
 0.944
EDS07477.1
HD domain protein; KEGG: ava:Ava_1777 4.6e-26 metal dependent phosphohydrolase, HD region with response regulator receiver modulation K07814; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.
 
     0.916
EDS07478.1
AMP-binding enzyme; KEGG: pca:Pcar_1619 7.6e-61 AMP-binding enzyme family protein K01897; COG: COG1022 Long-chain acyl-CoA synthetases (AMP-forming); Psort location: CytoplasmicMembrane, score: 9.49.
 
    0.853
EDS05532.1
Hypothetical protein; KEGG: dme:Dmel_CG15021 0.0090 CG15021 K04707; COG: NOG38544 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.738
EDS07438.1
Hypothetical protein; COG: NOG23664 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.679
acpP_3
KEGG: hpa:HPAG1_0538 2.3e-06 acyl carrier protein K01162; COG: COG0236 Acyl carrier protein; Psort location: Cytoplasmic, score: 8.87.
       0.650
XerC_5
Site-specific recombinase, phage integrase family; COG: COG0582 Integrase; Psort location: Cytoplasmic, score: 8.87.
  
     0.624
EDS06985.1
Hypothetical protein; KEGG: bfs:BF1664 4.3e-06 putative mannose-6-phosphate isomerase K01809; COG: NOG26319 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.621
kdpB
K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
  
  
 0.603
kdpC
K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
  
  
 0.603
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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