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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS07477.1HD domain protein; KEGG: ava:Ava_1777 4.6e-26 metal dependent phosphohydrolase, HD region with response regulator receiver modulation K07814; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87. (508 aa)    
Predicted Functional Partners:
FixL
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tma:TM1359 1.6e-21 sensor histidine kinase K02486; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.916
adrA
Diguanylate cyclase (GGDEF) domain protein; KEGG: shn:Shewana3_3829 1.9e-24 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
 0.900
ycdT
Diguanylate cyclase (GGDEF) domain protein; KEGG: eci:UTI89_C2343 2.6e-18 yegE; putative sensor-type protein; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
 0.869
SrfAA
AMP-binding enzyme; KEGG: ava:Ava_1613 5.8e-204 non-ribosomal peptide synthase K00644; COG: COG1020 Non-ribosomal peptide synthetase modules and related proteins; Psort location: Cytoplasmic, score: 9.96; Belongs to the ATP-dependent AMP-binding enzyme family.
 
    0.853
Cph2
Diguanylate cyclase (GGDEF) domain protein; KEGG: shn:Shewana3_3829 1.9e-35 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2200 FOG: EAL domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.830
EDS07478.1
AMP-binding enzyme; KEGG: pca:Pcar_1619 7.6e-61 AMP-binding enzyme family protein K01897; COG: COG1022 Long-chain acyl-CoA synthetases (AMP-forming); Psort location: CytoplasmicMembrane, score: 9.49.
 
     0.826
acpP_3
KEGG: hpa:HPAG1_0538 2.3e-06 acyl carrier protein K01162; COG: COG0236 Acyl carrier protein; Psort location: Cytoplasmic, score: 8.87.
       0.740
Gmr
Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VFA0796 2.2e-06 sensor protein; COG: COG2199 FOG: GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.709
EDS05417.1
Hypothetical protein; KEGG: shn:Shewana3_3829 0.0029 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.702
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.693
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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