Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
EDS07478.1AMP-binding enzyme; KEGG: pca:Pcar_1619 7.6e-61 AMP-binding enzyme family protein K01897; COG: COG1022 Long-chain acyl-CoA synthetases (AMP-forming); Psort location: CytoplasmicMembrane, score: 9.49. (550 aa)    
Predicted Functional Partners:
SrfAA
AMP-binding enzyme; KEGG: ava:Ava_1613 5.8e-204 non-ribosomal peptide synthase K00644; COG: COG1020 Non-ribosomal peptide synthetase modules and related proteins; Psort location: Cytoplasmic, score: 9.96; Belongs to the ATP-dependent AMP-binding enzyme family.
 
   
 0.893
FixL
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tma:TM1359 1.6e-21 sensor histidine kinase K02486; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.853
EDS07477.1
HD domain protein; KEGG: ava:Ava_1777 4.6e-26 metal dependent phosphohydrolase, HD region with response regulator receiver modulation K07814; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.
 
     0.821
acpP_3
KEGG: hpa:HPAG1_0538 2.3e-06 acyl carrier protein K01162; COG: COG0236 Acyl carrier protein; Psort location: Cytoplasmic, score: 8.87.
     
 0.799
Udk
Phosphoribulokinase/uridine kinase family protein; KEGG: ctc:CTC00344 2.9e-125 uridine kinase K00876; COG: COG0572 Uridine kinase; Psort location: Cytoplasmic, score: 8.87.
     
 0.701
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
   
 
 0.595
rplR
Ribosomal protein L18; KEGG: bma:BMA2191 0.0086 phosphoglucomutase/phosphomannomutase family protein K01835:K01840; COG: COG0256 Ribosomal protein L18; Psort location: Cytoplasmic, score: 8.87.
    
 
 0.591
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.580
BaiB
AMP-binding enzyme; KEGG: hne:HNE_0099 1.1e-68 baiB; bile acid-coenzyme A ligase; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: Cytoplasmic, score: 9.96.
 
 
 0.541
pncA
Isochorismatase family protein; KEGG: pab:PAB1720 3.7e-15 nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score: 8.87.
  
    0.480
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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