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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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luxSS-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (182 aa)    
Predicted Functional Partners:
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
 
 
 0.986
metH_3
KEGG: ctc:CTC01806 1.4e-203 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
    
 0.959
PatB
Aminotransferase, class I/II; KEGG: blo:BL1776 5.0e-146 probable aminotransferase K00842; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; Psort location: Cytoplasmic, score: 8.87.
     
 0.908
mgl_1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: bth:BT2387 1.2e-167 O-acetylhomoserine (thiol)-lyase K01740; COG: COG2873 O-acetylhomoserine sulfhydrylase; Psort location: Cytoplasmic, score: 9.98.
     
 0.903
mgl_2
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: bth:BT1923 8.7e-181 O-acetylhomoserine (thiol)-lyase K01740; COG: COG2873 O-acetylhomoserine sulfhydrylase; Psort location: Cytoplasmic, score: 9.98.
     
 0.903
cysK
Cysteine synthase A; KEGG: chy:CHY_0808 2.3e-102 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.878
cysK-2
Cysteine synthase A; KEGG: bld:BLi00089 7.0e-76 cysK; cysteine synthetase A; RBL03196 K01738; COG: COG0031 Cysteine synthase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.878
hom_2
KEGG: chy:CHY_1912 6.1e-125 hom; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
     
 0.807
hom_1
KEGG: tte:TTE2620 5.9e-79 thrA2; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
     
 0.807
ilvA
KEGG: fnu:FN1411 6.2e-116 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase.
     
  0.800
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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