Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; KEGG: fnu:FN0226 1.7e-122 pdxA; pyridoxal phosphate biosynthetic protein pdxA K00097; COG: COG1995 Pyridoxal phosphate biosynthesis protein; Psort location: Cytoplasmic, score: 8.87. (338 aa)    
Predicted Functional Partners:
EDS07490.1
Hypothetical protein; KEGG: ath:At1g18270 9.2e-09 T10O22.24; ketose-bisphosphate aldolase class-II family protein K00120; COG: COG3395 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
 
     0.945
gntT
Transporter, gluconate:H+ symporter family; KEGG: eci:UTI89_C3106 1.3e-60 ygbN; hypothetical permease YgbN K03299; COG: COG2610 H+/gluconate symporter and related permeases; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.905
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
     
 0.610
glpR_2
Transcriptional regulator, DeoR family; COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: Cytoplasmic, score: 8.87.
 
     0.585
EDS07489.1
Hypothetical protein; KEGG: ath:At1g18270 1.7e-84 T10O22.24; ketose-bisphosphate aldolase class-II family protein K00120; COG: KOG4153 Fructose 1,6-bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87.
 
     0.583
KdgT
Putative 2-keto-3-deoxygluconate transporter; COG: NOG06082 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.544
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.485
GarR_2
Putative 2-hydroxy-3-oxopropionate reductase; KEGG: sec:SC3195 1.9e-75 garR, tsaR; tartronate semialdehyde reductase (TSAR) K00042; COG: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
     0.472
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.443
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
      
 0.441
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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