close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gntTTransporter, gluconate:H+ symporter family; KEGG: eci:UTI89_C3106 1.3e-60 ygbN; hypothetical permease YgbN K03299; COG: COG2610 H+/gluconate symporter and related permeases; Psort location: CytoplasmicMembrane, score: 10.00. (467 aa)    
Predicted Functional Partners:
EDS07490.1
Hypothetical protein; KEGG: ath:At1g18270 9.2e-09 T10O22.24; ketose-bisphosphate aldolase class-II family protein K00120; COG: COG3395 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.930
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; KEGG: fnu:FN0226 1.7e-122 pdxA; pyridoxal phosphate biosynthetic protein pdxA K00097; COG: COG1995 Pyridoxal phosphate biosynthesis protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.911
glpR_2
Transcriptional regulator, DeoR family; COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.679
GarK
Glycerate kinase; KEGG: sak:SAK_0918 1.4e-109 glycerate kinase K00865; COG: COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family.
 
  
 0.659
FruA
KEGG: cpr:CPR_0550 3.4e-163 fructose specific permease K00890; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.631
EDS07489.1
Hypothetical protein; KEGG: ath:At1g18270 1.7e-84 T10O22.24; ketose-bisphosphate aldolase class-II family protein K00120; COG: KOG4153 Fructose 1,6-bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.556
GarR_2
Putative 2-hydroxy-3-oxopropionate reductase; KEGG: sec:SC3195 1.9e-75 garR, tsaR; tartronate semialdehyde reductase (TSAR) K00042; COG: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
  
 0.434
hisE
phosphoribosyl-ATP diphosphatase; KEGG: sao:SAOUHSC_03008 3.6e-56 imidazole glycerol phosphate synthase subunit HisF, putative K01663; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the PRA-PH family.
      
 0.416
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.