Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kdpBK+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (690 aa)    
Predicted Functional Partners:
kdpA
K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
 
 0.999
kdpC
K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
 
 0.997
kdpD_5
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lin:pli0050 9.7e-221 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.948
kdpE_4
Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 1.1e-47 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   
 0.797
kdpD_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: cac:CAC3678 1.5e-71 kdpD; sensor protein KdpD (ATPase containing sensor domain and histidine kinase domain) K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.734
kdpD_3
KEGG: lwe:lwe2628 9.5e-50 kdpD; sensor histidine kinase; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.97.
 
  
 0.697
EDS07503.1
Tetratricopeptide repeat protein.
       0.620
kdpD_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo2679 1.2e-63 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.598
aprX
Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family.
       0.597
EDS07510.1
Helix-turn-helix protein, YlxM/p13 family; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
       0.494
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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