| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aprX | ffh | CLOSCI_01318 | CLOSCI_01320 | Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.645 |
| aprX | kdpA | CLOSCI_01318 | CLOSCI_01313 | Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family. | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | 0.578 |
| aprX | kdpB | CLOSCI_01318 | CLOSCI_01314 | Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family. | K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. | 0.597 |
| aprX | kdpC | CLOSCI_01318 | CLOSCI_01315 | Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family. | K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. | 0.665 |
| aprX | kdpD_5 | CLOSCI_01318 | CLOSCI_01316 | Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lin:pli0050 9.7e-221 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.724 |
| aprX | kdpE_4 | CLOSCI_01318 | CLOSCI_01317 | Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family. | Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 1.1e-47 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.714 |
| ffh | aprX | CLOSCI_01320 | CLOSCI_01318 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family. | 0.645 |
| ffh | kdpA | CLOSCI_01320 | CLOSCI_01313 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | 0.479 |
| ffh | kdpB | CLOSCI_01320 | CLOSCI_01314 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. | 0.494 |
| ffh | kdpC | CLOSCI_01320 | CLOSCI_01315 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. | 0.543 |
| ffh | kdpD_5 | CLOSCI_01320 | CLOSCI_01316 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lin:pli0050 9.7e-221 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.613 |
| ffh | kdpE_4 | CLOSCI_01320 | CLOSCI_01317 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 1.1e-47 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.585 |
| kdpA | aprX | CLOSCI_01313 | CLOSCI_01318 | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family. | 0.578 |
| kdpA | ffh | CLOSCI_01313 | CLOSCI_01320 | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.479 |
| kdpA | kdpB | CLOSCI_01313 | CLOSCI_01314 | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. | 0.999 |
| kdpA | kdpC | CLOSCI_01313 | CLOSCI_01315 | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. | 0.999 |
| kdpA | kdpD_1 | CLOSCI_01313 | CLOSCI_03621 | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: cac:CAC3678 1.5e-71 kdpD; sensor protein KdpD (ATPase containing sensor domain and histidine kinase domain) K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.724 |
| kdpA | kdpD_5 | CLOSCI_01313 | CLOSCI_01316 | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lin:pli0050 9.7e-221 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.937 |
| kdpA | kdpE_1 | CLOSCI_01313 | CLOSCI_03622 | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 2.0e-48 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.517 |
| kdpA | kdpE_4 | CLOSCI_01313 | CLOSCI_01317 | K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 1.1e-47 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.803 |
