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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdpE_4Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 1.1e-47 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. (236 aa)    
Predicted Functional Partners:
kdpD_5
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lin:pli0050 9.7e-221 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
 
 0.995
kdpD_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: cac:CAC3678 1.5e-71 kdpD; sensor protein KdpD (ATPase containing sensor domain and histidine kinase domain) K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
 
 0.980
kdpC
K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.871
kdpA
K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.815
kdpB
K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.809
kdpD_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo2679 1.2e-63 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
 
 0.796
kdpD_3
KEGG: lwe:lwe2628 9.5e-50 kdpD; sensor histidine kinase; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.97.
 
 
 0.726
aprX
Peptidase, S8/S53 family; KEGG: mba:Mbar_A1626 6.2e-35 hypothetical protein; COG: COG1404 Subtilisin-like serine proteases; Psort location: Extracellular, score: 8.10; Belongs to the peptidase S8 family.
       0.714
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 0.685
phoR_5
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2750 8.8e-69 histidine kinase, putative; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
   0.631
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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