Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
lepB-2Signal peptidase I; KEGG: oih:OB1390 3.7e-22 sipS; signal peptidase I K03100; COG: COG0681 Signal peptidase I; Belongs to the peptidase S26 family. (197 aa)    
Predicted Functional Partners:
lepB-3
Signal peptidase I; KEGG: ctc:CTC01253 1.5e-27 putative signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.49; Belongs to the peptidase S26 family.
 
   
0.796
ylqF
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
    0.776
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.773
EDS07521.1
TIGR00252 family protein; KEGG: sat:SYN_00772 3.0e-20 endonuclease; COG: COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0102 family.
       0.723
yfiH
Conserved hypothetical protein, YfiH family; COG: COG1496 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the multicopper oxidase YfiH/RL5 family.
       0.657
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.616
mscS
COG: COG0668 Small-conductance mechanosensitive channel; Psort location: CytoplasmicMembrane, score: 10.00.
       0.592
rseP
RIP metalloprotease RseP; KEGG: cac:CAC1796 2.5e-64 predicted membrane-associated Zn-dependent protease; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1; Psort location: CytoplasmicMembrane, score: 7.63.
  
     0.455
trmD
tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
       0.439
EDS07368.1
MT-A70; KEGG: spj:MGAS2096_Spy1128 2.2e-56 adenine-specific methyltransferase K00571; COG: COG4725 Transcriptional activator, adenine-specific DNA methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the MT-A70-like family.
  
    0.408
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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