Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS07521.1TIGR00252 family protein; KEGG: sat:SYN_00772 3.0e-20 endonuclease; COG: COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0102 family. (118 aa)    
Predicted Functional Partners:
lepB-3
Signal peptidase I; KEGG: ctc:CTC01253 1.5e-27 putative signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.49; Belongs to the peptidase S26 family.
  
    0.803
ylqF
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
       0.790
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.790
yfiH
Conserved hypothetical protein, YfiH family; COG: COG1496 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the multicopper oxidase YfiH/RL5 family.
       0.771
ComM
Mg chelatase-like protein; KEGG: chu:CHU_0354 4.5e-120 ch1I; magnesium chelatase, subunit ChlI K07391; COG: COG0606 Predicted ATPase with chaperone activity; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.751
lepB-2
Signal peptidase I; KEGG: oih:OB1390 3.7e-22 sipS; signal peptidase I K03100; COG: COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
       0.723
mscS
COG: COG0668 Small-conductance mechanosensitive channel; Psort location: CytoplasmicMembrane, score: 10.00.
       0.676
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.669
dprA
DNA protecting protein DprA; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.646
yeaZ
Universal bacterial protein YeaZ; KEGG: ctc:CTC02444 6.5e-41 O-sialoglycoprotein endopeptidase K01409; COG: COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; Psort location: Cytoplasmic, score: 8.87.
 
     0.520
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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