STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfiHConserved hypothetical protein, YfiH family; COG: COG1496 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the multicopper oxidase YfiH/RL5 family. (277 aa)    
Predicted Functional Partners:
hpt
KEGG: tte:TTE2394 2.0e-53 hpt; hypoxanthine-guanine phosphoribosyltransferase K00760; COG: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
  0.917
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.904
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
    
  0.904
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
 0.904
xdhA
KEGG: mta:Moth_1960 4.8e-203 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K00087; COG: COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; Psort location: Cytoplasmic, score: 8.87.
    
  0.903
add
Adenosine deaminase; KEGG: hdu:HD0377 2.3e-86 add; probable adenosine deaminase K01488; COG: COG1816 Adenosine deaminase; Psort location: Cytoplasmic, score: 8.87.
    
  0.902
MtnA
eIF-2B alpha/beta/delta-related uncharacterized protein; KEGG: fnu:FN1413 9.4e-120 methylthioribose-1-phosphate isomerase K08963; COG: COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; Psort location: Cytoplasmic, score: 8.87; Belongs to the eIF-2B alpha/beta/delta subunits family.
    
  0.902
surE
KEGG: mth:MTH1435 4.0e-34 surE; acid phosphatase K03787; COG: COG0496 Predicted acid phosphatase; Psort location: Cytoplasmic, score: 8.87.
    
  0.901
deoD
KEGG: bcl:ABC4021 1.3e-76 deoD; purine-nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 8.87.
     
  0.900
mtnK
S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
     
  0.900
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.