Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
topB_3DNA topoisomerase; KEGG: cac:CAC3567 5.1e-105 topB; topoisomerase B K03169; COG: COG0550 Topoisomerase IA; Psort location: Cytoplasmic, score: 8.87. (679 aa)    
Predicted Functional Partners:
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
   0.805
recQ
KEGG: cpf:CPF_0327 4.3e-140 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.87.
 
 0.785
glmU_1
Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 2.4e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87.
 
     0.760
ppk1
Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
       0.720
garR_1
Phosphogluconate dehydrogenase (decarboxylating), NAD binding domain protein; KEGG: cpf:CPF_0381 7.2e-106 garR; 2-hydroxy-3-oxopropionate reductase K00042; COG: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Psort location: Cytoplasmic, score: 8.87.
       0.613
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.474
mgsA-2
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
     
 0.473
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
  
 0.472
asd
KEGG: lsl:LSL_0313 7.3e-145 asd; aspartate-semialdehyde dehydrogenase K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
       0.427
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.421
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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