Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PutPTransporter, SSS family; KEGG: rpr:RP465 0.0013 phoR; alkaline phosphatase synthesis sensor protein phoR K07636; COG: COG0591 Na+/proline symporter; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (516 aa)    
Predicted Functional Partners:
leuA
Putative 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
    0.564
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.449
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
   
  
 0.449
EDS08576.1
Hypothetical protein; KEGG: cpf:CPF_1123 1.3e-16 cell wall-associated serine proteinase K01361; COG: NOG17334 non supervised orthologous group.
  
     0.423
EDS07337.1
Hypothetical protein; COG: NOG31153 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.402
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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