Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
murRSIS domain protein; KEGG: bxe:Bxe_A3454 0.00072 glucokinase K00845; COG: COG1737 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. (310 aa)    
Predicted Functional Partners:
EDS07545.1
Flavoprotein family protein; KEGG: gox:GOX1717 3.3e-22 putative oxidoreductase K00100; COG: COG2081 Predicted flavoproteins.
       0.792
cmk
Cytidylate kinase; KEGG: ljo:LJ1089 2.3e-52 cytidylate kinase K00945; COG: COG0283 Cytidylate kinase; Psort location: Cytoplasmic, score: 8.87.
       0.734
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.646
rpsA_2
Putative ribosomal protein S1; KEGG: cno:NT01CX_2096 6.2e-68 RpsA K03527; COG: COG0761 Penicillin tolerance protein; Psort location: Cytoplasmic, score: 9.98.
       0.626
EDS07543.1
KEGG: tte:TTE1208 6.1e-148 pycA; Pyruvate carboxylase, C-terminal domain/subunit K01960; COG: COG5016 Pyruvate/oxaloacetate carboxyltransferase; Psort location: Cytoplasmic, score: 8.87.
       0.492
dnaC_1
Putative DNA replication protein DnaC; KEGG: spi:MGAS10750_Spy1680 6.7e-14 replicative DNA helicase K01529; COG: COG1484 DNA replication protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.483
gcdC
Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 3.5e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
 
     0.460
EDS06874.1
DnaD domain protein; COG: COG3935 Putative primosome component and related proteins; Psort location: Cytoplasmic, score: 8.87.
  
     0.455
gcdB
Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
       0.433
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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