Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
scpBSegregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (201 aa)    
Predicted Functional Partners:
scpA
ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.999
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.844
cmk
Cytidylate kinase; KEGG: ljo:LJ1089 2.3e-52 cytidylate kinase K00945; COG: COG0283 Cytidylate kinase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.774
rluF
KEGG: cpe:CPE2313 1.1e-61 pseudouridylate synthase K06182; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.
  
  
 0.678
EDS07576.1
Ser/Thr phosphatase family protein; KEGG: bce:BC2476 3.1e-34 phosphoesterase; COG: COG1408 Predicted phosphohydrolases; Psort location: Cytoplasmic, score: 8.87.
       0.672
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.658
topB_2
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
  
  
 0.658
RsuA
Pseudouridylate synthase; KEGG: tte:TTE0052 3.6e-63 rsuA; 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase K06183; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Psort location: Cytoplasmic, score: 8.87; Belongs to the pseudouridine synthase RsuA family.
  
  
 0.641
dacF_1
Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: tte:TTE1328 6.6e-48 dacC3; D-alanyl-D-alanine carboxypeptidase K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
    0.635
der
Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.608
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.