Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nifUFe-S iron-sulfur cluster assembly protein, NifU family; KEGG: rxy:Rxyl_1354 1.2e-21 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566; COG: COG0822 NifU homolog involved in Fe-S cluster formation; Psort location: Cytoplasmic, score: 8.87. (147 aa)    
Predicted Functional Partners:
nifS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 0.995
sufS_1
Cysteine desulfurase family protein; KEGG: mta:Moth_2214 4.7e-86 cysteine desulphurase related, unknown function K01763; COG: COG0520 Selenocysteine lyase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.986
iscS_2
Aminotransferase, class V; KEGG: tte:TTE1663 8.8e-101 nifS; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes K04487; COG: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
 
 0.979
EDS06715.1
SufB/sufD domain protein; COG: COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.922
mobA_3
Selenium-dependent molybdenum hydroxylase system protein, YqeB family; KEGG: hma:pNG7236 2.8e-14 glmU; UDP-N-acetylglucosamine pyrophosphorylase K00972; COG: COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.916
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.913
ecfA1_2
ABC transporter, ATP-binding protein; KEGG: syn:slr1455 1.5e-25 cysA; ABC-type sulfate transport system ATP-binding protein K02045; COG: COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
  
  
 0.910
sufS_2
Cysteine desulfurase family protein; KEGG: tde:TDE2460 1.5e-87 aminotransferase, class V; COG: COG0520 Selenocysteine lyase; Psort location: Cytoplasmic, score: 8.87.
  
 0.905
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
  
 0.864
CymR_2
Transcriptional regulator, Rrf2 family; KEGG: ama:AM656 9.9e-10 aminotransferase, class V K04487; COG: COG1959 Predicted transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.803
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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