| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bglK | nagA | CLOSCI_01433 | CLOSCI_01435 | ROK family protein; KEGG: spj:MGAS2096_Spy0236 3.9e-91 N-acetylmannosamine kinase / transcriptional regulator K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98. | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | 0.800 |
| bglK | nagB | CLOSCI_01433 | CLOSCI_03190 | ROK family protein; KEGG: spj:MGAS2096_Spy0236 3.9e-91 N-acetylmannosamine kinase / transcriptional regulator K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.412 |
| bglK | nanA | CLOSCI_01433 | CLOSCI_01429 | ROK family protein; KEGG: spj:MGAS2096_Spy0236 3.9e-91 N-acetylmannosamine kinase / transcriptional regulator K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98. | KEGG: spn:SP_1676 1.1e-118 N-acetylneuraminate lyase K01639; COG: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Psort location: Cytoplasmic, score: 8.87. | 0.711 |
| bglK | nanE | CLOSCI_01433 | CLOSCI_01428 | ROK family protein; KEGG: spj:MGAS2096_Spy0236 3.9e-91 N-acetylmannosamine kinase / transcriptional regulator K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98. | Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.772 |
| bglK | sglT | CLOSCI_01433 | CLOSCI_01430 | ROK family protein; KEGG: spj:MGAS2096_Spy0236 3.9e-91 N-acetylmannosamine kinase / transcriptional regulator K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98. | Transporter, SSS family; KEGG: rpr:RP465 2.5e-07 phoR; alkaline phosphatase synthesis sensor protein phoR K07636; COG: COG0591 Na+/proline symporter; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.722 |
| bglK | tabA | CLOSCI_01433 | CLOSCI_01431 | ROK family protein; KEGG: spj:MGAS2096_Spy0236 3.9e-91 N-acetylmannosamine kinase / transcriptional regulator K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98. | YhcH/YjgK/YiaL family protein; COG: COG2731 Beta-galactosidase, beta subunit; Psort location: Cytoplasmic, score: 8.87. | 0.806 |
| bglK | ybbH_3 | CLOSCI_01433 | CLOSCI_01434 | ROK family protein; KEGG: spj:MGAS2096_Spy0236 3.9e-91 N-acetylmannosamine kinase / transcriptional regulator K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98. | SIS domain protein; KEGG: cac:CAC0397 6.0e-08 predicted sugar phosphate aminotransferase involved in capsule formation K08094; COG: COG1737 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. | 0.793 |
| dapA | nanE | CLOSCI_03684 | CLOSCI_01428 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.495 |
| dctM | nagA | CLOSCI_02490 | CLOSCI_01435 | TRAP transporter, DctM subunit; COG: COG1593 TRAP-type C4-dicarboxylate transport system, large permease component; Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | 0.545 |
| dctM | nagB | CLOSCI_02490 | CLOSCI_03190 | TRAP transporter, DctM subunit; COG: COG1593 TRAP-type C4-dicarboxylate transport system, large permease component; Psort location: CytoplasmicMembrane, score: 9.99. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.551 |
| dctM | nanE | CLOSCI_02490 | CLOSCI_01428 | TRAP transporter, DctM subunit; COG: COG1593 TRAP-type C4-dicarboxylate transport system, large permease component; Psort location: CytoplasmicMembrane, score: 9.99. | Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.560 |
| dctM | nanK | CLOSCI_02490 | CLOSCI_02517 | TRAP transporter, DctM subunit; COG: COG1593 TRAP-type C4-dicarboxylate transport system, large permease component; Psort location: CytoplasmicMembrane, score: 9.99. | ROK family protein; KEGG: tte:TTE1961 1.6e-21 nagC4; transcriptional regulator K00845; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 8.87. | 0.499 |
| nagA | bglK | CLOSCI_01435 | CLOSCI_01433 | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | ROK family protein; KEGG: spj:MGAS2096_Spy0236 3.9e-91 N-acetylmannosamine kinase / transcriptional regulator K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98. | 0.800 |
| nagA | dctM | CLOSCI_01435 | CLOSCI_02490 | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | TRAP transporter, DctM subunit; COG: COG1593 TRAP-type C4-dicarboxylate transport system, large permease component; Psort location: CytoplasmicMembrane, score: 9.99. | 0.545 |
| nagA | nagB | CLOSCI_01435 | CLOSCI_03190 | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.999 |
| nagA | nanA | CLOSCI_01435 | CLOSCI_01429 | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | KEGG: spn:SP_1676 1.1e-118 N-acetylneuraminate lyase K01639; COG: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Psort location: Cytoplasmic, score: 8.87. | 0.735 |
| nagA | nanE | CLOSCI_01435 | CLOSCI_01428 | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.979 |
| nagA | nanK | CLOSCI_01435 | CLOSCI_02517 | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | ROK family protein; KEGG: tte:TTE1961 1.6e-21 nagC4; transcriptional regulator K00845; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 8.87. | 0.581 |
| nagA | sglT | CLOSCI_01435 | CLOSCI_01430 | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | Transporter, SSS family; KEGG: rpr:RP465 2.5e-07 phoR; alkaline phosphatase synthesis sensor protein phoR K07636; COG: COG0591 Na+/proline symporter; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.608 |
| nagA | tabA | CLOSCI_01435 | CLOSCI_01431 | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | YhcH/YjgK/YiaL family protein; COG: COG2731 Beta-galactosidase, beta subunit; Psort location: Cytoplasmic, score: 8.87. | 0.555 |