Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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Textmining
[Homology]
Score
dcm-2KEGG: cac:CAC1222 4.8e-100 DNA-methyltransferase (cytosine-specific) K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87. (324 aa)    
Predicted Functional Partners:
hpaIIM
Modification methylase HpaII; KEGG: mpe:MYPE9800 3.9e-75 cytosine-specific DNA methylase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.
 
  
0.941
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.908
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.901
dcm
DNA (cytosine-5-)-methyltransferase; KEGG: san:gbs1370 1.3e-37 similar to methyl transferase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
   
 0.791
parA
CobQ/CobB/MinD/ParA nucleotide binding domain protein; KEGG: cch:Cag_1803 5.1e-25 ATPase, ParA family K03496; COG: COG1192 ATPases involved in chromosome partitioning; Psort location: Cytoplasmic, score: 8.87.
       0.773
EDS07377.1
Hypothetical protein.
       0.773
EDS07375.1
Hypothetical protein.
       0.658
EDS07373.1
VRR-NUC domain protein.
       0.629
EDS07374.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.624
vsr
DNA mismatch endonuclease Vsr; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
   
 0.612
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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