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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpP-3KEGG: lsl:LSL_0785 2.8e-24 clpP; ATP-dependent Clp protease proteolytic subunit K01358; COG: COG0740 Protease subunit of ATP-dependent Clp proteases; Psort location: Cytoplasmic, score: 8.87; Belongs to the peptidase S14 family. (275 aa)    
Predicted Functional Partners:
EDS07390.1
Phage portal protein, HK97 family; COG: COG4695 Phage-related protein.
 
  
 0.901
EDS07389.1
COG: COG4626 Phage terminase-like protein, large subunit; Psort location: Cytoplasmic, score: 8.87.
 
     0.872
clpX-2
KEGG: bcz:BCZK4216 6.6e-96 clpX; ATP-dependent Clp protease, ATP-binding subunit K03544; COG: COG1219 ATP-dependent protease Clp, ATPase subunit; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.854
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 
 
 0.848
EDS07388.1
COG: COG3747 Phage terminase, small subunit; Psort location: Cytoplasmic, score: 8.87.
 
    0.840
EDS07392.1
Phage major capsid protein, HK97 family; COG: NOG26567 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
    0.813
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.731
clpC
ATPase family associated with various cellular activities (AAA); KEGG: sab:SAB0475 4.3e-227 clpC; endopeptidase K03696; COG: COG0542 ATPases with chaperone activity, ATP-binding subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the ClpA/ClpB family.
  
 
 0.731
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.662
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
   
  
 0.640
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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