Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
queG4Fe-4S binding domain protein; COG: COG1600 Uncharacterized Fe-S protein; Psort location: Cytoplasmic, score: 8.87. (225 aa)    
Predicted Functional Partners:
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
  
 0.765
nnr
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
     
 0.641
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
     
 0.517
EDS07427.1
Hypothetical protein; KEGG: cpf:CPF_0724 0.0084 acetyltransferase, GNAT family K03826; COG: NOG36299 non supervised orthologous group.
       0.501
YvbK_1
Acetyltransferase, GNAT family; KEGG: fnu:FN1384 3.0e-43 IAA acetyltransferase K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score: 8.87.
       0.501
metH_3
KEGG: ctc:CTC01806 1.4e-203 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
     
 0.485
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
    0.449
EDS07710.1
Hypothetical protein; KEGG: tfu:Tfu_0134 0.0010 inorganic H+ pyrophosphatase K01507; COG: COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.429
hemE_3
Hypothetical protein; KEGG: mmp:MMP0831 4.3e-16 mtbA; uroporphyrinogen decarboxylase (URO-D) K00599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87.
 
     0.422
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.