| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS07204.1 | EDS07206.1 | CLOSCI_01547 | CLOSCI_01549 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | PAP2 family protein; KEGG: eci:UTI89_C1633 2.9e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.97. | 0.856 |
| EDS07204.1 | cdsA | CLOSCI_01547 | CLOSCI_02030 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | KEGG: ctc:CTC01266 1.2e-48 phosphatidate cytidylyltransferase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDS family. | 0.928 |
| EDS07204.1 | cysE | CLOSCI_01547 | CLOSCI_01225 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | KEGG: gka:GK0084 1.1e-63 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98. | 0.803 |
| EDS07204.1 | glyA | CLOSCI_01547 | CLOSCI_00072 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
| EDS07204.1 | ilvA | CLOSCI_01547 | CLOSCI_00627 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | KEGG: fnu:FN1411 6.2e-116 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | 0.901 |
| EDS07204.1 | pgsA | CLOSCI_01547 | CLOSCI_00669 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: tte:TTE1376 7.5e-40 pgsA2; Phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.929 |
| EDS07204.1 | pgsA_1 | CLOSCI_01547 | CLOSCI_03659 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | CDP-alcohol phosphatidyltransferase; KEGG: ctc:CTC00117 2.3e-22 phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.942 |
| EDS07204.1 | psd | CLOSCI_01547 | CLOSCI_01546 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | KEGG: cac:CAC0799 6.4e-50 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Psort location: Cytoplasmic, score: 8.87. | 0.995 |
| EDS07204.1 | sdaAA | CLOSCI_01547 | CLOSCI_02322 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | KEGG: ljo:LJ1328 9.2e-58 L-serine dehydratase alpha subunit K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.911 |
| EDS07204.1 | sdaAB | CLOSCI_01547 | CLOSCI_02323 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | KEGG: btk:BT9727_3885 1.7e-51 sdhB; L-serine dehydratase, beta subunit K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
| EDS07206.1 | EDS07204.1 | CLOSCI_01549 | CLOSCI_01547 | PAP2 family protein; KEGG: eci:UTI89_C1633 2.9e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.97. | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | 0.856 |
| EDS07206.1 | psd | CLOSCI_01549 | CLOSCI_01546 | PAP2 family protein; KEGG: eci:UTI89_C1633 2.9e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.97. | KEGG: cac:CAC0799 6.4e-50 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Psort location: Cytoplasmic, score: 8.87. | 0.843 |
| cdsA | EDS07204.1 | CLOSCI_02030 | CLOSCI_01547 | KEGG: ctc:CTC01266 1.2e-48 phosphatidate cytidylyltransferase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDS family. | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | 0.928 |
| cdsA | pgsA | CLOSCI_02030 | CLOSCI_00669 | KEGG: ctc:CTC01266 1.2e-48 phosphatidate cytidylyltransferase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDS family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: tte:TTE1376 7.5e-40 pgsA2; Phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.934 |
| cdsA | pgsA_1 | CLOSCI_02030 | CLOSCI_03659 | KEGG: ctc:CTC01266 1.2e-48 phosphatidate cytidylyltransferase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDS family. | CDP-alcohol phosphatidyltransferase; KEGG: ctc:CTC00117 2.3e-22 phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.917 |
| cysE | EDS07204.1 | CLOSCI_01225 | CLOSCI_01547 | KEGG: gka:GK0084 1.1e-63 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98. | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97. | 0.803 |
| cysE | glyA | CLOSCI_01225 | CLOSCI_00072 | KEGG: gka:GK0084 1.1e-63 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.842 |
| cysE | ilvA | CLOSCI_01225 | CLOSCI_00627 | KEGG: gka:GK0084 1.1e-63 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98. | KEGG: fnu:FN1411 6.2e-116 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | 0.810 |
| cysE | sdaAA | CLOSCI_01225 | CLOSCI_02322 | KEGG: gka:GK0084 1.1e-63 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98. | KEGG: ljo:LJ1328 9.2e-58 L-serine dehydratase alpha subunit K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.912 |
| cysE | sdaAB | CLOSCI_01225 | CLOSCI_02323 | KEGG: gka:GK0084 1.1e-63 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98. | KEGG: btk:BT9727_3885 1.7e-51 sdhB; L-serine dehydratase, beta subunit K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.912 |