STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (321 aa)    
Predicted Functional Partners:
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); KEGG: fnu:FN0010 2.0e-85 nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score: 9.98; Belongs to the NadC/ModD family.
 
 
 0.999
NadB
FAD binding domain protein; KEGG: fnu:FN0009 4.8e-100 L-aspartate oxidase K00278; COG: COG0029 Aspartate oxidase; Psort location: Cytoplasmic, score: 9.36.
 
 0.999
niaR
HTH domain protein; KEGG: mac:MA0676 2.3e-06 bpl, birA; biotin operon repressor/biotin-pyruvate carboxylase ligase K03524:K01947; COG: COG1827 Predicted small molecule binding protein (contains 3H domain); Psort location: Cytoplasmic, score: 8.87.
 
  
 0.800
pnuC
COG: COG3201 Nicotinamide mononucleotide transporter; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.763
opuBA
Hypothetical protein; KEGG: pen:PSEEN3440 7.1e-10 ABC transporter, ATP-binding protein; COG: COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; Psort location: Cytoplasmic, score: 8.87.
       0.762
cysE
KEGG: gka:GK0084 1.1e-63 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98.
  
    0.750
valS
valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
      0.657
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.631
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.613
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.608
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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