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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lepB-4KEGG: spb:M28_Spy0108 2.1e-21 signal peptidase I K03100; Psort location: Cytoplasmic, score: 8.87; Belongs to the peptidase S26 family. (179 aa)    
Predicted Functional Partners:
EDS07262.1
Pilin isopeptide linkage domain protein; KEGG: cal:orf19.4072 0.0010 HYR10; similar to cell surface flocculin K01186.
 
     0.805
EDS07264.1
Von Willebrand factor type A domain protein; KEGG: lpl:lp_3093 0.0012 muramidase (putative) K01185; COG: NOG22929 non supervised orthologous group.
       0.775
EDS07260.1
Hypothetical protein.
 
     0.719
srtB-2
Sortase, SrtB family; COG: COG4509 Uncharacterized protein conserved in bacteria.
 
     0.686
minE
Putative cell division topological specificity factor MinE; Psort location: Cytoplasmic, score: 8.87.
   
    0.648
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
  
 0.550
EDS07857.1
Pilin isopeptide linkage domain protein.
 
     0.496
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
    0.452
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
   
    0.445
phoU
Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.445
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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