Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bssDGlycyl-radical enzyme activating protein family protein; KEGG: tko:TK0290 4.0e-57 pyruvate-formate lyase-activating enzyme K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.98. (302 aa)    
Predicted Functional Partners:
cutC_1
Putative formate C-acetyltransferase; KEGG: gsu:GSU2101 4.5e-239 formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.971
cutC_2
Pyruvate formate lyase; KEGG: cno:NT01CX_0385 3.9e-59 pyruvate formate-lyase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.873
pflB-2
KEGG: cya:CYA_0477 9.2e-264 pflB; formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.808
pflB
KEGG: bce:BC0491 6.8e-268 formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.801
AdhE
Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.673
hndC_3
4Fe-4S binding domain protein; KEGG: swo:Swol_1701 3.0e-194 NADH dehydrogenase (quinone) K05903; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
      
 0.659
cobU_2
Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; KEGG: cps:CPS_3657 1.9e-18 cobP; bifunctional cobalamin biosynthesis protein CobP K02231; COG: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 8.87.
   
    0.649
YccX
Acylphosphatase; KEGG: cpe:CPE1973 3.8e-13 probable acylphosphatase K01512; COG: COG1254 Acylphosphatases; Psort location: Cytoplasmic, score: 8.87.
       0.517
qacR
Transcriptional regulator, TetR family; KEGG: bha:BH3415 2.2e-06 NADH dehydrogenase K03885; COG: NOG38850 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.515
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
     
 0.508
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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