Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
swrCRND transporter, HAE1/HME family, permease protein; KEGG: eci:UTI89_C2351 1.8e-66 yegO; hypothetical protein YegO K07789; COG: COG0841 Cation/multidrug efflux pump; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1271 aa)    
Predicted Functional Partners:
mdtA
Efflux transporter, RND family, MFP subunit; KEGG: cal:orf19.7201 0.00079 SLA2; structural constituent of cytoskeleton K00870; COG: COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.896
EDS08196.1
Hypothetical protein.
  
 
 0.879
spoT
HD domain protein; KEGG: sat:SYN_03611 5.4e-30 GTP pyrophosphokinase / guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase K00951:K01139; COG: COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; Psort location: Cytoplasmic, score: 8.87.
     
 0.739
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
  
 0.649
EDS07302.1
Hypothetical protein; COG: NOG10026 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.589
fabG_1
Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: ctc:CTC00798 2.3e-54 3-oxoacyl-[acyl-carrier-protein] reductase K00059; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score: 9.98; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.573
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
   
 
 0.530
scpA
ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.497
bmr3_3
Transporter, major facilitator family protein; KEGG: tdn:Tmden_0898 0.0010 protein-disulfide reductase K04084; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.496
yajC
COG: COG1862 Preprotein translocase subunit YajC.
   
 
 0.485
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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