| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS07039.1 | resE_7 | CLOSCI_01699 | CLOSCI_01695 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.746 |
| EDS07039.1 | tctD | CLOSCI_01699 | CLOSCI_01696 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | Transcriptional regulatory protein, C-terminal domain protein; KEGG: rha:RHA1_ro05622 5.6e-09 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 8.87. | 0.746 |
| EDS07039.1 | walR_6 | CLOSCI_01699 | CLOSCI_01697 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | Response regulator receiver domain protein; KEGG: eci:UTI89_C4496 1.2e-14 cpxR; transcriptional regulatory protein CpxR K07662; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.762 |
| EDS07039.1 | xpt | CLOSCI_01699 | CLOSCI_01698 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.762 |
| MprB | PhoP_5 | CLOSCI_03930 | CLOSCI_00655 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.785 |
| MprB | SrrA_4 | CLOSCI_03930 | CLOSCI_00498 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | KEGG: eci:UTI89_C2354 7.9e-29 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.630 |
| MprB | mprA_1 | CLOSCI_03930 | CLOSCI_03915 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | KEGG: rha:RHA1_ro05622 1.5e-34 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65. | 0.592 |
| MprB | walR_6 | CLOSCI_03930 | CLOSCI_01697 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: eci:UTI89_C4496 1.2e-14 cpxR; transcriptional regulatory protein CpxR K07662; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.757 |
| MprB | walR_7 | CLOSCI_03930 | CLOSCI_00239 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Transcriptional regulatory protein, C-terminal domain protein; KEGG: ava:Ava_3369 8.5e-16 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.422 |
| PhoP_5 | MprB | CLOSCI_00655 | CLOSCI_03930 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.785 |
| PhoP_5 | resE_7 | CLOSCI_00655 | CLOSCI_01695 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.685 |
| PhoP_5 | srrB_2 | CLOSCI_00655 | CLOSCI_03726 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 1.6e-39 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.674 |
| PhoP_5 | walR_6 | CLOSCI_00655 | CLOSCI_01697 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | Response regulator receiver domain protein; KEGG: eci:UTI89_C4496 1.2e-14 cpxR; transcriptional regulatory protein CpxR K07662; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.761 |
| SrrA_4 | MprB | CLOSCI_00498 | CLOSCI_03930 | KEGG: eci:UTI89_C2354 7.9e-29 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.630 |
| SrrA_4 | resE_7 | CLOSCI_00498 | CLOSCI_01695 | KEGG: eci:UTI89_C2354 7.9e-29 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.486 |
| SrrA_4 | srrB_2 | CLOSCI_00498 | CLOSCI_03726 | KEGG: eci:UTI89_C2354 7.9e-29 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 1.6e-39 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.557 |
| SrrA_4 | walR_6 | CLOSCI_00498 | CLOSCI_01697 | KEGG: eci:UTI89_C2354 7.9e-29 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | Response regulator receiver domain protein; KEGG: eci:UTI89_C4496 1.2e-14 cpxR; transcriptional regulatory protein CpxR K07662; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.764 |
| SrrA_4 | walR_7 | CLOSCI_00498 | CLOSCI_00239 | KEGG: eci:UTI89_C2354 7.9e-29 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | Transcriptional regulatory protein, C-terminal domain protein; KEGG: ava:Ava_3369 8.5e-16 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.733 |
| mprA_1 | MprB | CLOSCI_03915 | CLOSCI_03930 | KEGG: rha:RHA1_ro05622 1.5e-34 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.592 |
| mprA_1 | resE_7 | CLOSCI_03915 | CLOSCI_01695 | KEGG: rha:RHA1_ro05622 1.5e-34 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.480 |