| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS07039.1 | EDS07040.1 | CLOSCI_01699 | CLOSCI_01700 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.436 |
| EDS07039.1 | immR_8 | CLOSCI_01699 | CLOSCI_03697 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | DNA-binding helix-turn-helix protein; COG: COG1396 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. | 0.679 |
| EDS07039.1 | resE_7 | CLOSCI_01699 | CLOSCI_01695 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.746 |
| EDS07039.1 | tctD | CLOSCI_01699 | CLOSCI_01696 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | Transcriptional regulatory protein, C-terminal domain protein; KEGG: rha:RHA1_ro05622 5.6e-09 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 8.87. | 0.746 |
| EDS07039.1 | walR_6 | CLOSCI_01699 | CLOSCI_01697 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | Response regulator receiver domain protein; KEGG: eci:UTI89_C4496 1.2e-14 cpxR; transcriptional regulatory protein CpxR K07662; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.762 |
| EDS07039.1 | xpt | CLOSCI_01699 | CLOSCI_01698 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.762 |
| EDS07039.1 | yknY_2 | CLOSCI_01699 | CLOSCI_01694 | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | KEGG: fal:FRAAL5379 2.8e-40 ABC transporter ATP-binding protein K06020; COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49. | 0.498 |
| EDS07040.1 | EDS07039.1 | CLOSCI_01700 | CLOSCI_01699 | EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | 0.436 |
| EDS07040.1 | resE_7 | CLOSCI_01700 | CLOSCI_01695 | EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.423 |
| EDS07040.1 | tctD | CLOSCI_01700 | CLOSCI_01696 | EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Transcriptional regulatory protein, C-terminal domain protein; KEGG: rha:RHA1_ro05622 5.6e-09 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 8.87. | 0.490 |
| EDS07040.1 | walR_6 | CLOSCI_01700 | CLOSCI_01697 | EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Response regulator receiver domain protein; KEGG: eci:UTI89_C4496 1.2e-14 cpxR; transcriptional regulatory protein CpxR K07662; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.431 |
| EDS07040.1 | xpt | CLOSCI_01700 | CLOSCI_01698 | EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.431 |
| immR_8 | EDS07039.1 | CLOSCI_03697 | CLOSCI_01699 | DNA-binding helix-turn-helix protein; COG: COG1396 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | 0.679 |
| resE_7 | EDS07039.1 | CLOSCI_01695 | CLOSCI_01699 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | 0.746 |
| resE_7 | EDS07040.1 | CLOSCI_01695 | CLOSCI_01700 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.423 |
| resE_7 | tctD | CLOSCI_01695 | CLOSCI_01696 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Transcriptional regulatory protein, C-terminal domain protein; KEGG: rha:RHA1_ro05622 5.6e-09 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 8.87. | 0.893 |
| resE_7 | walR_6 | CLOSCI_01695 | CLOSCI_01697 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: eci:UTI89_C4496 1.2e-14 cpxR; transcriptional regulatory protein CpxR K07662; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.937 |
| resE_7 | xpt | CLOSCI_01695 | CLOSCI_01698 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.757 |
| resE_7 | yknY_2 | CLOSCI_01695 | CLOSCI_01694 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | KEGG: fal:FRAAL5379 2.8e-40 ABC transporter ATP-binding protein K06020; COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49. | 0.763 |
| tctD | EDS07039.1 | CLOSCI_01696 | CLOSCI_01699 | Transcriptional regulatory protein, C-terminal domain protein; KEGG: rha:RHA1_ro05622 5.6e-09 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 8.87. | DNA-binding helix-turn-helix protein; KEGG: par:Psyc_0717 0.0039 putative aminotransferase K00812; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.97. | 0.746 |