STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
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[Homology]
Score
scrKKinase, PfkB family; KEGG: ath:At1g06030 1.4e-63 T21E18.8; pfkB-type carbohydrate kinase family protein K00847; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score: 9.98. (320 aa)    
Predicted Functional Partners:
FruA
KEGG: cpr:CPR_0550 3.4e-163 fructose specific permease K00890; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.939
pgi
KEGG: bcl:ABC2906 1.4e-164 pgi; glucose-6-phosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.98; Belongs to the GPI family.
  
 
 0.909
pfp_1
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.907
pfp_2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.907
pfkA-2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 0.907
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.907
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
 0.907
gatD
GroES-like protein; KEGG: lin:lin0506 1.3e-65 similar to polyol (sorbitol) dehydrogenase K00008; COG: KOG0024 Sorbitol dehydrogenase; Psort location: Cytoplasmic, score: 9.65.
    
 0.904
gutB
L-iditol 2-dehydrogenase; KEGG: rde:RD1_0514 2.3e-38 gutB; sorbitol dehydrogenase, putative K00008; COG: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98.
  
 
  0.903
yjmD
Putative chlorophyll synthesis pathway protein BchC; KEGG: tde:TDE0075 1.0e-76 sorbitol dehydrogenase, putative K00008; COG: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98.
  
 
  0.903
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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