Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDS07091.1Malic enzyme, NAD binding domain protein; KEGG: tte:TTE2332 9.9e-125 sfcA; malic enzyme K00027; COG: COG0281 Malic enzyme; Psort location: CytoplasmicMembrane, score: 9.97. (382 aa)    
Predicted Functional Partners:
pyk-2
Pyruvate kinase; KEGG: tte:TTE1815 8.7e-133 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
  
 0.967
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.960
fumB
Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; KEGG: chy:CHY_1374 5.7e-58 fumarate hydratase, beta subunit K01678; COG: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.955
PrpC2
KEGG: lla:L67186 6.4e-137 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.948
FumA
KEGG: wsu:WS1767 1.5e-38 fumB_beta; fumarate hydratase B, beta subunit K01678; COG: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.
 
 
 0.940
ttdA
Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; KEGG: cac:CAC3091 8.4e-96 fumarate hydratase, subunit A (N-terminal domain of FumA E.coli) class I K01677; COG: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.936
pyk
Pyruvate kinase; KEGG: tte:TTE1815 1.2e-137 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
  
 0.933
pta
Phosphate acetyltransferase; KEGG: hhe:HH1309 1.1e-100 pta; phosphotransacetylase K00625; COG: COG0280 Phosphotransacetylase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.931
ppdK
Pyruvate, phosphate dikinase; KEGG: tte:TTE0981 0. ppsA2; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01006; COG: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Psort location: Cytoplasmic, score: 9.98; Belongs to the PEP-utilizing enzyme family.
  
 
 0.927
gcdB
Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
    
 0.914
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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