close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WalK_3ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo2500 3.6e-47 phoR; two-component sensor histidine kinase K07636; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. (454 aa)    
Predicted Functional Partners:
EDS07102.1
Hypothetical protein; COG: NOG17868 non supervised orthologous group.
 
    0.945
walR_5
Response regulator receiver domain protein; KEGG: ava:Ava_1878 9.1e-51 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
   0.929
comEC_1
DNA internalization competence protein ComEC/Rec2-like protein; COG: COG0658 Predicted membrane metal-binding protein; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.878
srrA_3
Response regulator receiver domain protein; KEGG: ava:Ava_1878 6.3e-43 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
   0.819
srrA_1
Response regulator receiver domain protein; KEGG: fal:FRAAL1628 2.9e-47 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 0.792
phoP_4
Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.4e-35 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
   0.766
cseB
Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.3e-37 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
   0.761
walR_2
Response regulator receiver domain protein; KEGG: fal:FRAAL1628 6.2e-36 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65.
 
 
 0.760
srrA_2
Response regulator receiver domain protein; KEGG: ava:Ava_3369 5.4e-46 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
   0.759
WalR_1
Response regulator receiver domain protein; KEGG: ava:Ava_3369 5.4e-46 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 0.728
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (30%) [HD]